Observations on the Nature, Causes and Treatment of Beriberi
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Adolphe Vorderman's 1897 study on beriberi: an example of scrupulous efforts to avoid bias.
This paper highlights Adolphe Vorderman’s investigations of the causes of beriberi using epidemiological observations among prison inmates in the Dutch East Indies (today Indonesia) in the 1890s. His investigations are featured in the James Lind Library because of Vorderman’s scrupulous efforts to avoid bias. He built a number of methodological safeguards into his investigations, both to avoid ...
متن کاملCase report: pericardial effusion with constrictive physiology in a patient with wet beriberi
Wet beriberi-induced pericardial effusion has rarely been previously described. Little is known about the effect of beriberi-induced pericardial effusion on hemodynamics. Here we present a case of wet beriberi with pericardial effusion that exhibited constrictive physiology, which was dramatically improved after treatment. A 61-year-old male patient was admitted to our hospital for progressive ...
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Previous studies have suggested that diuretic therapy for heart failure may lead to thiamine deficiency due to the increased urinary thiamine excretion. Herein, we present the case of a 61-year-old man with shoshin beriberi, a fulminant form of wet beriberi, induced by long-term diuretic therapy. The patient had a history of heart failure with preserved ejection fraction and was receiving furos...
متن کاملClinical History and Colliquative Myocytolysis Are Keys to the Diagnosis of Shoshin Beriberi
Cardiovascular beriberi presents as either the fulminant (Shoshin beriberi) or chronic form. Shoshin beriberi is a rare disease that may lead to a fatal outcome if the patient does not receive appropriate treatment. In the present report, we describe the case of a 66-year-old man presenting with leg edema and dyspnea at rest. Clinical presentations were nonalcoholic Shoshin beriberi and lactate...
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Autoimmune diseases have been described as an interesting and poorly understood group of disorders. There are many challenges in the respective scientific societies concerning the nature, causes and the therapeutic approaches of these diseases. In accordance with the evidences the nature and etiology of these disorders is multifactorial and complex but the clearest definition could be expressed...
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